Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809585 | 0.77 | PDCD1 (0.38) | PDCD1CD274DPP4ALDH1A1HSD17B10 | |
| SCHEMBL9806251 | 0.65 | PDCD1 (0.47) | PDCD1CD274DPP4ALDH1A1HSD17B10 | |
| SCHEMBL4620488 | 0.64 | PDCD1 (0.36) | PDCD1CD274DPP4ALDH1A1HSD17B10 | |
| SCHEMBL2850867 | 0.64 | PDCD1 (0.36) | PDCD1CD274DPP4ALDH1A1HSD17B10 | |
| SCHEMBL27304686 | 0.64 | DPP4 (0.58) | PDCD1CD274DPP4ALDH1A1HSD17B10 | |
| SCHEMBL1583270 | 0.63 | DPP4 (0.39) | PDCD1CD274DPP4 | |
| Butane SCHEMBL15105003 | 0.62 | PTGS2 (0.48) | PDCD1CD274DPP4ALDH1A1HSD17B10 | |
| SCHEMBL328862 | 0.61 | DPP4 (0.60) | PDCD1CD274DPP4ALDH1A1HSD17B10 | |
| SCHEMBL31261742 | 0.61 | DPP4 (0.60) | PDCD1CD274DPP4ALDH1A1HSD17B10 | |
| SCHEMBL9717406 | 0.61 | PDCD1 (0.47) | PDCD1CD274DPP4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262197-B1 | AS POLYMERIZATION CATALYST IN OLEFIN POLYMERIZATION | TARGOR GMBH (DE) | 2001-07-17 | — | — | US | claimed |
| US-6262197-B1 | AS POLYMERIZATION CATALYST IN OLEFIN POLYMERIZATION | TARGOR GMBH (DE) | 2001-07-17 | — | — | US | disclosed |
| EP-0739897-A1 | Polynuclear metallocene compound, process for preparing it and its use as catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-30 | — | — | EP | disclosed |