Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942083 | 0.86 | TSHR (0.43) | TSHRPOLBGABRA1GABRB2ALDH1A1 | |
| SCHEMBL7950209 | 0.82 | TSHR (0.45) | TSHRLTB4RLTB4R2GABRA1GABRB2 | |
| SCHEMBL2021180 | 0.78 | TSHR (0.56) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL1836388 | 0.76 | GABRA1 (0.42) | GABRA1GABRB2 | |
| SCHEMBL2022076 | 0.75 | TSHR (0.63) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL7942081 | 0.74 | TSHR (0.44) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL248040 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2022485 | 0.74 | TSHR (0.58) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL5684896 | 0.74 | TSHR (0.46) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL5951024 | 0.73 | TSHR (0.46) | TSHRMAPK1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197918-B1 | INTERCHANGE REACTION OF DIALKYL CARBONATE AND AROMATIC ALCOHOL; CATALYSIS WITH TITANIUM HALIDE, ALKOXIDE, ARYLOXIDE, OR ACETOXIDE | GENERAL ELECTRIC COMPANY | 2001-03-06 | — | — | US | disclosed |