Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942081 | 0.85 | TSHR (0.44) | TSHRGABRA1GABRB2CA12CA1 | |
| SCHEMBL2021180 | 0.84 | TSHR (0.56) | TSHRGABRA1GABRB2CA12CA1 | |
| SCHEMBL7950211 | 0.82 | TSHR (0.45) | TSHRGABRA1GABRB2LTB4RLTB4R2 | |
| SCHEMBL5684896 | 0.82 | TSHR (0.46) | TSHRGABRA1GABRB2MAPTHTT | |
| SCHEMBL5951024 | 0.81 | TSHR (0.46) | TSHRGABRA1GABRB2CA12CA1 | |
| SCHEMBL2022485 | 0.80 | TSHR (0.58) | TSHRGABRA1GABRB2PTPN2PTPN1 | |
| SCHEMBL2022076 | 0.78 | TSHR (0.63) | TSHRGABRA1GABRB2PTPN2PTPN1 | |
| SCHEMBL988680 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2MAPTL3MBTL1NPSR1 | |
| SCHEMBL29580903 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2MAPTL3MBTL1NPSR1 | |
| SCHEMBL1841644 | 0.76 | L3MBTL1 (0.42) | TSHRGABRA1GABRB2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197918-B1 | INTERCHANGE REACTION OF DIALKYL CARBONATE AND AROMATIC ALCOHOL; CATALYSIS WITH TITANIUM HALIDE, ALKOXIDE, ARYLOXIDE, OR ACETOXIDE | GENERAL ELECTRIC COMPANY | 2001-03-06 | — | — | US | disclosed |