Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23882900 | 0.83 | POLB (0.35) | MAPTHSD17B10KDM4EUBE2NTDP1 | |
| SCHEMBL30251155 | 0.83 | POLB (0.35) | MAPTHSD17B10KDM4EUBE2NTDP1 | |
| SCHEMBL10607897 | 0.79 | MAPT (0.40) | MAPTHSD17B10KDM4EUBE2NHMGB1 | |
| SCHEMBL865601 | 0.78 | MEN1 (0.36) | HSD17B10TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL20554715 | 0.76 | ALDH1A1 (0.52) | MAPTHSD17B10KDM4ETDP1ALDH1A1 | |
| SCHEMBL30132596 | 0.76 | ALDH1A1 (0.52) | MAPTHSD17B10KDM4ETDP1ALDH1A1 | |
| SCHEMBL30132562 | 0.75 | SHBG (0.55) | MAPTHSD17B10ALDH1A1ALOX15MEN1 | |
| SCHEMBL20554833 | 0.75 | SHBG (0.55) | MAPTHSD17B10ALDH1A1ALOX15MEN1 | |
| SCHEMBL15483655 | 0.74 | ALDH1A1 (0.40) | MAPTHSD17B10KDM4EUBE2NHMGB1 | |
| SCHEMBL4126506 | 0.72 | HMGB1 (0.57) | MAPTHSD17B10KDM4EHMGB1CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258827-B1 | HYDROXYAROMATIC HETEROCYCLIC ALKANOLS AND LEVODOPA | PFIZER INC. | 2001-07-10 | — | — | US | disclosed |
| US-6046213-A | Neuroprotective 3-(piperidinyl-1)-chroman-4,7-diol and 1-(4-hydroxyphenyl)-2-(piperidinyl-1)-alkanol derivatives | PFIZER INC. (US) | 2000-04-04 | — | — | US | disclosed |