Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395983 | 0.86 | MRGPRX4 (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL11262011 | 0.86 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL2775176 | 0.86 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL7948551 | 0.86 | USP2 (0.36) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL7948556 | 0.83 | USP2 (0.36) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL7942174 | 0.83 | NR3C1 (0.38) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL29789565 | 0.83 | APEX1 (0.38) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL1705525 | 0.83 | APEX1 (0.38) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL10442446 | 0.83 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL29367415 | 0.82 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36128-E | STABILIZER FOR ORGANIC COMPOUNDS | ALBEMARLE CORPORATION (US) | 1999-03-02 | — | — | US | claimed |
| EP-0280938-B1 | Antioxidant aromatic fluorophosphites | ETHYL CORP (US) | 1994-06-15 | — | — | EP | claimed |
| US-4912155-A | Containing substituted aryl group | ETHYL CORPORATION (US) | 1990-03-27 | — | — | US | claimed |
| EP-0280938-A1 | Antioxidant aromatic fluorophosphites | ALBEMARLE CORPORATION (US) | 1988-09-07 | — | — | EP | claimed |
| CN-1293941-C | Hydroformylation process using novel phosphite-metal catalyst system | EASTMAN CHEM CO (US) | 2007-01-10 | — | — | CN | disclosed |
| US-6231804-B1 | USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |
| CN-1270544-A | Hydroformylation process using novel phosphite-metal catalyst system | EASTMAN CHEM CO (US) | 2000-10-18 | — | — | CN | disclosed |
| EP-0972800-A1 | MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING | CHISSO CORPORATION (JP) | 2000-01-19 | — | — | EP | disclosed |