Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 3/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SNRNP200 | O75643 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175725 | 0.90 | ALDH1A1 (0.53) | ALDH1A1TSHREPHX2GAACRBN | |
| SCHEMBL6176414 | 0.87 | EPHX2 (0.41) | ALDH1A1TSHREPHX2GAAAKT1 | |
| SCHEMBL7950687 | 0.83 | GAA (0.40) | ALDH1A1TSHREPHX2GAAPIM1 | |
| SCHEMBL6176303 | 0.82 | GAA (0.40) | ALDH1A1TSHREPHX2GAAPIM1 | |
| SCHEMBL7950898 | 0.82 | HTT (0.43) | ALDH1A1EPHX2GAASMN1; SMN2 | |
| SCHEMBL7959374 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TSHREPHX2GAASMN1; SMN2 | |
| SCHEMBL6177881 | 0.80 | GAA (0.38) | ALDH1A1TSHREPHX2GAAPIM1 | |
| SCHEMBL7950643 | 0.80 | GAA (0.38) | ALDH1A1TSHREPHX2GAAPIM1 | |
| SCHEMBL6179125 | 0.80 | EPHX2 (0.39) | ALDH1A1TSHREPHX2GAAPIM1 | |
| SCHEMBL7950813 | 0.79 | GAA (0.37) | ALDH1A1TSHREPHX2GAAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |