Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176414 | 0.85 | EPHX2 (0.41) | HTTSMN1; SMN2ALDH1A1GAAEPHX2 | |
| SCHEMBL7950687 | 0.84 | GAA (0.40) | ALDH1A1GAAEPHX2MAPTKDM4E | |
| SCHEMBL6176303 | 0.83 | GAA (0.40) | ALDH1A1GAAEPHX2MAPTKDM4E | |
| SCHEMBL7959374 | 0.82 | ALDH1A1 (0.43) | HTTSMN1; SMN2ALDH1A1GAAEPHX2 | |
| SCHEMBL7959365 | 0.82 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9AGAAEPHX2 | |
| SCHEMBL7950474 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1GAAEPHX2 | |
| SCHEMBL6179125 | 0.81 | EPHX2 (0.39) | ALDH1A1BRD4GAAEPHX2MAPT | |
| SCHEMBL7950643 | 0.81 | GAA (0.38) | ALDH1A1GAAEPHX2MAPTKDM4E | |
| SCHEMBL6177881 | 0.81 | GAA (0.38) | ALDH1A1BRD4GAAEPHX2MAPT | |
| SCHEMBL7950813 | 0.80 | GAA (0.37) | ALDH1A1GAAEPHX2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |