SCHEMBL79505

SCHEMBL79505

CC1c2ccc(NCc3ccccc3)cc2Nc2cc(NCc3ccccc3)ccc21

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.47
OPRD1 P41143 3/20 0.45
OPRM1 P35372 2/20 0.45
OPRK1 P41145 2/20 0.45
PTPN1 P18031 1/20 0.43
PTPN11 Q06124 1/20 0.43
METAP2 P50579 1/20 0.42
FFAR1 O14842 2/20 0.41
FFAR4 Q5NUL3 1/20 0.41
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
IP6K1 Q92551 1/20 0.40
BRD4 O60885 1/20 0.40
HAO1 Q9UJM8 1/20 0.40
HTR2C P28335 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
NR3C1 P04150 1/20 0.40
DHFR P00374 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6690772 0.72 HTT (0.57) HTTPTPN1PTPN11METAP2FFAR1
SCHEMBL3890165 0.72 HTT (0.50) HTTPTPN1PTPN11FFAR1FFAR4
SCHEMBL6482475 0.72 NOX1 (0.51) HTTPTPN1PTPN11MAOBMAOA
SCHEMBL11516173 0.71 HTT (0.46) HTTOPRD1OPRM1OPRK1PTPN1
SCHEMBL1924100 0.70 HTT (0.78) HTTPTPN1PTPN11FFAR1FFAR4
SCHEMBL6495200 0.69 HSD17B3 (0.48) HTTPTPN1PTPN11MAOBMAOA
SCHEMBL73008 0.68 HTT (0.53) HTTPTPN1PTPN11METAP2FFAR1
SCHEMBL11176623 0.68 MAPT (0.65) HTTPTPN1PTPN11MAOBCA1
SCHEMBL259701 0.68 MAPT (0.65) HTT
SCHEMBL20804371 0.68 HTT (0.61) HTTPTPN1PTPN11FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8127675-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-7662540-B2 Support, photosensitive layer, protective film; photosensitive layer and protective film being formed in this order on support, wherein number of fish-eyes each having area of 2,000 mu m2 or more and maximum height measured from film surface of 1 mu m to 7 mu m residing in film is 50/m2-1,000/m2 FUJIFILM CORPORATION (JP) 2010-02-16 US disclosed
US-20100005989-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION 2010-01-14 US disclosed
US-7556911-B2 Titanocene based compound, photosensitive composition, photosensitive transfer sheet and pattern forming method FUJIFILM CORPORATION (JP) 2009-07-07 US disclosed
EP-1765592-B1 METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2009-01-28 EP disclosed
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
US-20080268374-A1 Photosensitive Composition, Pattern Forming Material, Photosensitive Laminate, Pattern Forming Apparatus, and Pattern Forming Process FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-7402374-B2 Method for colored image formation FUJIFILM CORPORATION (JP) 2008-07-22 US disclosed
US-20080118867-A1 Pattern Forming Material, Pattern Forming Apparatus, And Pattern Forming Process ASAHI KASEI E-MATERIALS CORPORATION (JP) 2008-05-22 US disclosed
US-20080113302-A1 Pattern Forming Process FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed
US-20030232193-A1 Dry film resist and printed circuit board producing method FUJI PHOTO FILM CO., LTD. (JP) 2003-12-18 US disclosed
US-5030548-A Photoiniator system comprising a 4,4'-bis(dialkylamino) benzophenone, an aromatic ketone and lophine dimer; also present a halogen compound leuco and dye; lithography; printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-07-09 US disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4271251-A LEUCO DYE, PHOTOOXIDIZER, 2,4-DIHYDROXY-BENZALDOXIME FUJI PHOTO FILM CO., LTD. (JP) 1981-06-02 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed