Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | METAP2 | P50579 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20804371 | 0.90 | HTT (0.61) | HTTPTPN1PTPN11FFAR1KCNH3 | |
| SCHEMBL22628164 | 0.87 | HTT (0.71) | HTTPTPN1PTPN11FFAR1KCNH3 | |
| N-Benzylaniline SCHEMBL7840 | 0.87 | HTT (0.71) | HTTPTPN1PTPN11FFAR1KCNH3 | |
| SCHEMBL15463279 | 0.87 | METAP2 (0.62) | HTTMETAP2PTPN1PTPN11FFAR1 | |
| SCHEMBL28855181 | 0.87 | FFAR1 (0.53) | HTTMETAP2PTPN1PTPN11FFAR1 | |
| SCHEMBL10054970 | 0.86 | HDAC8 (0.61) | HTTFFAR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL259701 | 0.86 | MAPT (0.65) | HTTMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21477257 | 0.86 | METAP2 (0.49) | HTTMETAP2PTPN1PTPN11FFAR1 | |
| SCHEMBL1681160 | 0.86 | HTR6 (0.54) | HTTMETAP2PTPN1PTPN11FFAR1 | |
| SCHEMBL1965560 | 0.86 | FFAR1 (0.51) | HTTMETAP2PTPN1PTPN11FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974699-A | Preparation method of aromatic diamine | 江苏湘园化工有限公司 | 2023-04-18 | — | — | CN | disclosed |
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | PAH, PNMT, OPRM1 | HTT 2301/4885METAP2 1031/4885PTPN1 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.