Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736432 | 0.89 | ALDH1A1 (0.59) | AKR1C3ALDH1A1SMN1; SMN2HPGDHDAC8 | |
| SCHEMBL9876838 | 0.88 | AKR1C3 (0.64) | AKR1C3ALDH1A1SMN1; SMN2HDAC8ERCC5 | |
| SCHEMBL257820 | 0.85 | HPGD (0.54) | AKR1C3ALDH1A1SMN1; SMN2HPGDHDAC8 | |
| SCHEMBL20812516 | 0.84 | AKR1C3 (0.58) | AKR1C3ALDH1A1SMN1; SMN2HPGDHDAC8 | |
| SCHEMBL11486845 | 0.84 | SMN1; SMN2 (0.85) | ALDH1A1SMN1; SMN2HPGDERCC5FEN1 | |
| SCHEMBL9182454 | 0.83 | AKR1C3 (0.57) | AKR1C3ALDH1A1SMN1; SMN2HDAC8ERCC5 | |
| SCHEMBL15577951 | 0.82 | F10 (0.49) | AKR1C3ALDH1A1SMN1; SMN2HPGDHDAC8 | |
| SCHEMBL29386478 | 0.82 | F10 (0.49) | AKR1C3ALDH1A1SMN1; SMN2HPGDHDAC8 | |
| SCHEMBL2540656 | 0.82 | CES2 (0.67) | SMN1; SMN2F10NPC1 | |
| SCHEMBL30870831 | 0.82 | CES2 (0.67) | SMN1; SMN2F10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021717-A2 | HCV PROTEASE INHIBITORS | SEQUOIA PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| US-4208205-A | Herbicidal benzamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4124370-A | Diphenyl ethers for tobacco sucker control | ROHM AND HAAS COMPANY (US) | 1978-11-07 | — | — | US | disclosed |