Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043772 | 0.97 | KDM4E (0.38) | KDM4EL3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL7952511 | 0.84 | ALDH1A1 (0.50) | KDM4EL3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL8049613 | 0.81 | ATM (0.42) | KDM4EL3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL13099782 | 0.81 | CCNT1 (0.39) | JAK2JAK1JAK3PIK3CBIGF1R | |
| SCHEMBL7942597 | 0.80 | CCNT1 (0.40) | KMT2AMEN1CASP1HSD17B10CYP1A2 | |
| SCHEMBL8041792 | 0.79 | PIK3CB (0.43) | MAPK1CYP3A4JAK2JAK1PIK3CB | |
| SCHEMBL7954528 | 0.78 | CCNT1 (0.41) | KDM4EL3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL13099796 | 0.78 | ALDH1A1 (0.49) | KDM4EL3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL8049619 | 0.78 | KDM4E (0.39) | KDM4EL3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL13099812 | 0.78 | PIK3CB (0.38) | KDM4EL3MBTL1ATMMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027114-A1 | USE OF PYRAZOLE-PYRIDINE DERIVATIVES AND ITS SALTS FOR TREATING OR REVENTIN OSTEOPOROSIS | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-11 | — | — | WO | disclosed |
| WO-2009038385-A2 | NOVEL COMPOUNDS HAVING INDAZOLE FRAMEWORKS, METHODS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHOONGWAE PHARMA CORPORATION (KR) | 2009-03-26 | — | — | WO | disclosed |