Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 3/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954537 | 0.90 | MAPK1 (0.49) | PIK3CBMAPK1JAK2IGF1RPRMT5 | |
| SCHEMBL8034850 | 0.90 | PIK3CB (0.40) | PIK3CBMAPK1JAK2DYRK1AADORA2A | |
| SCHEMBL13099810 | 0.86 | PIK3CB (0.41) | PIK3CBMAPK1JAK2IGF1RPRMT5 | |
| SCHEMBL7953230 | 0.85 | PIK3CB (0.44) | PIK3CBMAPK1JAK2IGF1REGFR | |
| SCHEMBL7952511 | 0.80 | ALDH1A1 (0.50) | PIK3CBMAPK1CYP3A4 | |
| SCHEMBL7950686 | 0.79 | KDM4E (0.38) | PIK3CBMAPK1JAK2IGF1RCYP3A4 | |
| SCHEMBL8043772 | 0.78 | KDM4E (0.38) | PIK3CBMAPK1JAK2IGF1RCYP3A4 | |
| SCHEMBL3239677 | 0.76 | MAPK1 (0.36) | PIK3CBMAPK1EGFRAKT1AKT2 | |
| SCHEMBL8049613 | 0.76 | ATM (0.42) | PIK3CBMAPK1JAK2IGF1REGFR | |
| SCHEMBL7955207 | 0.74 | ALDH1A1 (0.37) | MAPK1DYRK1AADORA2APRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038385-A2 | NOVEL COMPOUNDS HAVING INDAZOLE FRAMEWORKS, METHODS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHOONGWAE PHARMA CORPORATION (KR) | 2009-03-26 | — | — | WO | disclosed |