Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 11/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178904 | 0.94 | CCKBR (0.49) | CCKBRMAPTCYP3A4TSHR | |
| SCHEMBL6196286 | 0.93 | CCKBR (0.41) | CCKBRMAPTCYP3A4TSHRPOLB | |
| SCHEMBL6177496 | 0.91 | CCKBR (0.48) | CCKBRMAPTCYP3A4TSHRPOLB | |
| SCHEMBL7965743 | 0.91 | CCKBR (0.49) | CCKBRMAPTCYP3A4TSHR | |
| SCHEMBL6177002 | 0.90 | CCKBR (0.47) | CCKBRMAPTCYP3A4TSHRPOLB | |
| SCHEMBL6179079 | 0.89 | CCKBR (0.49) | CCKBRMAPTCYP3A4TSHRPOLB | |
| SCHEMBL6192423 | 0.89 | CCKBR (0.47) | CCKBRMAPTCYP3A4TSHR | |
| SCHEMBL6176935 | 0.89 | CCKBR (0.46) | CCKBRMAPTCYP3A4TSHRPOLB | |
| SCHEMBL6176442 | 0.88 | RAB9A (0.44) | CCKBRMAPTCYP3A4TSHRPOLB | |
| SCHEMBL6176419 | 0.88 | CCKBR (0.45) | CCKBRMAPTCYP3A4TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |