SCHEMBL7950805

SCHEMBL7950805

NC(=O)CC(S)S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5867412 0.80 TDP1 (0.37)
SCHEMBL11204402 0.75
SCHEMBL17130392 0.75
SCHEMBL3069492 0.75
SCHEMBL10427592 0.73
SCHEMBL27729988 0.73
SCHEMBL12085019 0.72 LMNA (0.41)
SCHEMBL13741006 0.71
SCHEMBL22387072 0.69 ALOX15 (0.34)
SCHEMBL5581336 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018102554-A1 CLEAVABLE NUCLEOTIDE ANALOGS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2018-06-07 WO claimed
CN-103319433-A Production technology of CMI (cell-mediated immunity) industrial antibacterial agent WANG JIANGUO 2013-09-25 CN claimed
CN-103319433-A Production technology of CMI (cell-mediated immunity) industrial antibacterial agent WANG JIANGUO 2013-09-25 CN disclosed
CN-1294991-C Liposome composition for improved intracellular delivery of therapeutic agent ALZA CORP (US) 2007-01-17 CN disclosed
CN-1509166-A Liposome composition for improved intracellular delivery of therapeutic agent 2004-06-30 CN disclosed
CN-1426467-A Thrombopoietin receptor modulating peptide PLIVA PHARM & CHEM WORKS (HR) 2003-06-25 CN disclosed
US-6265519-B1 CURING AN EPOXIDE MOLEX INCORPORATED 2001-07-24 US disclosed
EP-0108633-B1 ASSAY FOR QUALITATIVELY AND/OR QUANTITATIVELY MEASURING HLH OR HCG IN BODY FLUIDS AND REAGENTS THEREFOR CORNELL RESEARCH FOUNDATION, INC. (US) 1991-02-13 EP disclosed
CN-1041359-A PROCESS FOR PREPARING LEUKOTRIENE ANTAGONIST PRODRUGS SMITHKLINE BECKMAN CORP (US) 1990-04-18 CN disclosed
US-4880914-A COMMON RECEPTOR FOR BOTH HORMONES CORNELL RESEARCH FOUNDATION, INC. 1989-11-14 US disclosed
US-4560649-A COMPLEXING WITH DISULFIDE COMPOUND CORNELL RESEARCH FOUNDATION (US) 1985-12-24 US disclosed
EP-0108633-A2 Assay for qualitatively and/or quantitatively measuring hLH or hCG in body fluids and reagents therefor CORNELL RESEARCH FOUNDATION, INC. (US) 1984-05-16 EP disclosed