Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MGLL | Q99685 | 4/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651582 | 0.88 | ALDH1A1 (0.58) | ALDH1A1MGLLFAAHKMT2AMEN1 | |
| SCHEMBL7949290 | 0.85 | KMT2A (0.60) | KMT2AMAPTHTR2CHRH3MLNR | |
| Hydrochloric Acid SCHEMBL1788931 | 0.84 | KMT2A (0.59) | KMT2AMAPTHTR2CHRH3MLNR | |
| SCHEMBL1984815 | 0.82 | MGLL (0.53) | ALDH1A1MGLLFAAHKMT2AMEN1 | |
| SCHEMBL3088167 | 0.79 | NQO1 (0.56) | ALDH1A1MGLLFAAHKMT2AMEN1 | |
| SCHEMBL3920889 | 0.77 | KMT2A (0.59) | ALDH1A1MGLLFAAHKMT2AMEN1 | |
| SCHEMBL1787312 | 0.76 | MEN1 (0.51) | ALDH1A1MGLLFAAHKMT2AMEN1 | |
| SCHEMBL14710213 | 0.75 | MGLL (0.58) | ALDH1A1MGLLFAAHKMT2AMEN1 | |
| SCHEMBL1859601 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MGLLFAAHKMT2AMEN1 | |
| SCHEMBL12651589 | 0.74 | KMT2A (0.63) | KMT2AMAPTHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007382-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HSTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED. (JP) | 2010-01-21 | — | — | WO | disclosed |