Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950930 | 1.00 | ACE (0.51) | ACE | |
| SCHEMBL31092820 | 0.95 | ACE (0.55) | ACE | |
| SCHEMBL705456 | 0.95 | ACE (0.55) | ACE | |
| SCHEMBL3702462 | 0.95 | ACE (0.55) | ACE | |
| SCHEMBL927332 | 0.95 | ACE (0.55) | ACE | |
| SCHEMBL29545684 | 0.95 | ACE (0.55) | ACE | |
| SCHEMBL29443087 | 0.95 | ACE (0.55) | ACE | |
| SCHEMBL7957322 | 0.88 | DRD2 (0.47) | — | |
| SCHEMBL17031897 | 0.84 | NOTUM (0.44) | ACE | |
| SCHEMBL17032680 | 0.84 | NOTUM (0.50) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258815-B1 | HETEROCYCLIC COMPOUNDS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | claimed |
| US-6258815-B1 | HETEROCYCLIC COMPOUNDS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |