Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827020 | 0.95 | DRD2 (0.51) | DRD2DRD4ELANEPTPN1NOTUM | |
| SCHEMBL29442998 | 0.95 | DRD2 (0.51) | DRD2DRD4ELANEPTPN1NOTUM | |
| SCHEMBL2827018 | 0.95 | DRD2 (0.51) | DRD2DRD4ELANEPTPN1NOTUM | |
| SCHEMBL7950933 | 0.88 | ACE (0.51) | — | |
| SCHEMBL7950930 | 0.88 | ACE (0.51) | — | |
| SCHEMBL20220810 | 0.85 | NOTUM (0.44) | NOTUM | |
| SCHEMBL21490396 | 0.84 | KMT2A (0.46) | DRD2DRD4PTPN1 | |
| SCHEMBL29443080 | 0.84 | KMT2A (0.46) | DRD2DRD4PTPN1 | |
| SCHEMBL927332 | 0.82 | ACE (0.55) | — | |
| SCHEMBL31092820 | 0.82 | ACE (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258815-B1 | HETEROCYCLIC COMPOUNDS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |