Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495527 | 0.83 | TP53 (0.35) | LMNAPKMALDH1A1HPGDMAPT | |
| SCHEMBL537494 | 0.80 | KMT2A (0.38) | LMNAALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL909187 | 0.80 | KMT2A (0.38) | LMNAALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL909752 | 0.80 | KMT2A (0.38) | LMNAALDH1A1HPGDHSD17B10EPHX2 | |
| SCHEMBL32681961 | 0.79 | SLC6A2 (0.37) | LMNASLC6A2ALDH1A1EPHX2MEN1 | |
| SCHEMBL19947479 | 0.79 | EPHX2 (0.36) | LMNAEPHX2KMT2ATSHR | |
| SCHEMBL19947480 | 0.79 | EPHX2 (0.36) | LMNAEPHX2KMT2ATSHR | |
| SCHEMBL27206070 | 0.78 | KDM4E (0.39) | LMNAPKMALDH1A1HPGDMAPT | |
| SCHEMBL3812470 | 0.77 | MEN1 (0.34) | LMNAMAOAALDH1A1MEN1KMT2A | |
| SCHEMBL3809686 | 0.77 | MEN1 (0.34) | LMNAMAOAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277868-B1 | BACTERICIDES; SKIN DISORDERS | ABBOTT LABORATORIES | 2001-08-21 | — | — | US | disclosed |