SCHEMBL19947480

SCHEMBL19947480

Cc1ccc(S(=O)(=O)O)c(CC2CCC(=O)O2)c1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 14/20 0.36
CYP1A2 P05177 2/20 0.35
KMT2A Q03164 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19947479 1.00 EPHX2 (0.36) EPHX2CYP1A2KMT2ANCOA3LMNA
SCHEMBL32681961 0.82 SLC6A2 (0.37) EPHX2KMT2ANCOA3LMNATSHR
SCHEMBL27206070 0.81 KDM4E (0.39) EPHX2KMT2ANCOA3LMNATSHR
SCHEMBL909187 0.81 KMT2A (0.38) EPHX2KMT2ANCOA3LMNATSHR
SCHEMBL537494 0.81 KMT2A (0.38) EPHX2KMT2ANCOA3LMNATSHR
SCHEMBL909752 0.81 KMT2A (0.38) EPHX2KMT2ANCOA3LMNATSHR
SCHEMBL4305143 0.79 PTGS2 (0.39)
SCHEMBL7951069 0.79 LMNA (0.43) EPHX2KMT2ALMNATSHR
SCHEMBL965090 0.78 KDM4E (0.46) KMT2ATSHR
SCHEMBL2484468 0.78 KDM4E (0.46) KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3280704-B1 METHOD FOR SYNTHESIZING A PRECURSOR OF A SINGLE DAIRY-LACTONE ISOMER INST DES SCIENCES ET INDUSTRIES DU VIVANT ET DE LENVIRONNEMENT AGROPARISTECH (FR) 2019-06-12 EP disclosed
US-10183923-B2 Method for synthesizing a precursor of a single dairy-lactone isomer INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT—AGROPARIS TECH (FR) 2019-01-22 US disclosed
US-20180072693-A1 METHOD FOR SYNTHESIZING A PRECURSOR OF A SINGLE DAIRY-LACTONE ISOMER INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT - AGROPARIS TECH (FR) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180072693-A1 METHOD FOR SYNTHESIZING A PRECURSOR OF A SINGLE DAIRY-LACTONE ISOMER DDOST, PTMS, DCXR EPHX2 941/4885CYP1A2 1400/4885KMT2A 3711/4885
US-10183923-B2 Method for synthesizing a precursor of a single dairy-lactone isomer DDOST, PTMS, DCXR EPHX2 941/4885CYP1A2 1400/4885KMT2A 3711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.