Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | USP25 | Q9UHP3 | 4/20 | 0.35 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467234 | 0.82 | CHEK1 (0.39) | FPR2SCN9AHRH4HRH3CHEK1 | |
| SCHEMBL1693574 | 0.82 | FPR2 (0.39) | FPR2SCN9AHRH4HRH3CHEK1 | |
| SCHEMBL1694252 | 0.81 | CYP1A2 (0.37) | FPR2SCN9ACHEK1KCNH2LSS | |
| SCHEMBL656257 | 0.78 | GFER (0.53) | CNR2GPR55KIT | |
| SCHEMBL653761 | 0.75 | HRH4 (0.41) | FPR2SCN9AHRH4HRH3CHEK1 | |
| SCHEMBL655042 | 0.72 | HRH4 (0.61) | HRH4CNR2HRH3KCNH2 | |
| SCHEMBL660185 | 0.70 | CYP2D6 (0.41) | HRH4CNR2 | |
| SCHEMBL653372 | 0.70 | CNR2 (0.48) | HRH4CNR2GPR55 | |
| SCHEMBL4778347 | 0.69 | HRH4 (0.43) | FPR2SCN9AHRH4HRH3KCNH2 | |
| SCHEMBL653760 | 0.69 | KDM4E (0.50) | HRH4CNR2GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616077-A1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2013-07-24 | — | — | EP | disclosed |
| EP-2575969-A1 | ANTIVIRAL ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2013-04-10 | — | — | EP | disclosed |
| WO-2012035423-A1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2012-03-22 | — | — | WO | disclosed |