⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152967 | 0.88 | — | — | |
| SCHEMBL13717499 | 0.86 | TP53 (0.41) | — | |
| SCHEMBL133227 | 0.86 | TP53 (0.41) | — | |
| SCHEMBL14997062 | 0.82 | IDO1 (0.37) | — | |
| SCHEMBL24245491 | 0.77 | — | — | |
| SCHEMBL3538774 | 0.75 | ALOX5 (0.41) | — | |
| SCHEMBL3924280 | 0.73 | — | — | |
| SCHEMBL7502308 | 0.73 | ANPEP (0.32) | — | |
| SCHEMBL1337717 | 0.73 | — | — | |
| SCHEMBL7514984 | 0.73 | ANPEP (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198292-B2 | Vinpocetine and eburnamonine derivatives for promoting bone growth, treating renal damage and cancer, and devices thereof | OSTEOGENEX, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20100003324-A1 | VINPOCETINE AND EBURN AMONINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOGENEX INC. (US) | 2010-01-07 | — | — | US | disclosed |
| WO-2010002835-A2 | VINPOCETINE AND EBURNAMONINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOGENEX, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| US-4102890-A | HYPNOTIC, ANALGESIC, HYPOTENSIVE, CARDIOVASCULAR DEPRESSANTS, NEURO-MODULATORS | SCIENCE-UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1978-07-25 | — | — | US | disclosed |