Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12128787 | 0.79 | HRH4 (0.33) | HRH4HRH3 | |
| SCHEMBL7571286 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL12310216 | 0.67 | HRH4 (0.34) | HRH4HRH3 | |
| SCHEMBL8006199 | 0.62 | — | — | |
| SCHEMBL24256050 | 0.57 | FUCA1 (0.50) | — | |
| SCHEMBL15267212 | 0.57 | LRAT (0.37) | — | |
| SCHEMBL24198606 | 0.57 | LRAT (0.37) | — | |
| SCHEMBL13746073 | 0.57 | LRAT (0.37) | — | |
| SCHEMBL24265064 | 0.57 | LRAT (0.37) | — | |
| SCHEMBL13890067 | 0.57 | LRAT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9271993-B2 | Treatment of bacterial infectious diseases | UNIVERSITY OF ZURICH (CH) | 2016-03-01 | — | — | US | disclosed |
| EP-2616079-B1 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES | UNIV ZÜRICH (CH) | 2015-10-14 | — | — | EP | disclosed |
| EP-2616079-A1 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES | University of Zürich (CH) | 2013-07-24 | — | — | EP | disclosed |
| US-20130165397-A1 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES | ETH ZURICH (CH) | 2013-06-27 | — | — | US | disclosed |
| WO-2012034955-A1 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES | UNIVERSITY OF ZURICH (CH) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165397-A1 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES | APRT, BPGM, TLR5 | HRH4 1579/4885HRH3 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.