Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808759 | 0.81 | TAAR1 (0.52) | TAAR1CYP3A4ALDH1A1HSD17B10POLB | |
| SCHEMBL7139460 | 0.81 | TAAR1 (0.57) | TAAR1CYP3A4ALDH1A1POLBKDM4E | |
| SCHEMBL394300 | 0.78 | TAAR1 (0.76) | TAAR1ALDH1A1HSD17B10TDP1POLB | |
| SCHEMBL30487922 | 0.76 | TAAR1 (0.73) | TAAR1ALDH1A1HSD17B10TDP1POLB | |
| SCHEMBL3778217 | 0.74 | PTGES2 (0.54) | TAAR1CYP3A4ALDH1A1POLBKDM4E | |
| SCHEMBL3778213 | 0.74 | PTGES2 (0.54) | TAAR1CYP3A4ALDH1A1POLBKDM4E | |
| SCHEMBL5891023 | 0.73 | ALDH1A1 (0.60) | CYP3A4ALDH1A1HSD17B10TDP1LMNA | |
| SCHEMBL150162 | 0.73 | ALDH1A1 (0.60) | CYP3A4ALDH1A1HSD17B10TDP1LMNA | |
| SCHEMBL1478175 | 0.73 | TAAR1 (0.61) | TAAR1CYP3A4ALDH1A1HSD17B10TDP1 | |
| SCHEMBL343986 | 0.72 | NOTUM (0.61) | CYP3A4ALDH1A1POLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1286812-C | Bispiperidines as antithrombotic agents | LINRAH RES LAB CO LTD (FR) | 2006-11-29 | — | — | CN | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |
| CN-1312799-A | Bispiperidines as antithrombotic agents | L LAB (FR) | 2001-09-12 | — | — | CN | disclosed |