Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LPL | P06858 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517779 | 0.83 | PTGS2 (0.68) | PTGS2USP2L3MBTL1 | |
| SCHEMBL7951850 | 0.81 | TAAR1 (0.52) | TAAR1CYP3A4LPLLIPGUSP2 | |
| SCHEMBL7139460 | 0.81 | TAAR1 (0.57) | TAAR1PTGS2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6516395 | 0.81 | TAAR1 (0.48) | TAAR1CYP3A4USP2L3MBTL1KDM4E | |
| SCHEMBL6514434 | 0.81 | PTGS2 (0.67) | PTGS2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6512690 | 0.81 | PTGS2 (0.46) | PTGS2 | |
| SCHEMBL6517008 | 0.81 | PTGS2 (0.46) | PTGS2 | |
| SCHEMBL6511607 | 0.81 | PTGS2 (0.72) | PTGS2USP2L3MBTL1KMT2A | |
| SCHEMBL6516399 | 0.81 | GRIN2B (0.43) | TAAR1PTGS2CYP3A4USP2L3MBTL1 | |
| SCHEMBL7517944 | 0.79 | KIF11 (0.47) | PTGS2CYP3A4KDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103442568-A | Furo [3,2-d ] pyrimidine compounds | ABBVIE INC | 2013-12-11 | — | — | CN | disclosed |