SCHEMBL7951883

SCHEMBL7951883

CC(C)(C)OC(=O)NC1CCN(Cc2cccc(N)n2)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.52
CHRM1 P11229 2/20 0.52
CHRM3 P20309 2/20 0.52
KCNA3 P22001 1/20 0.50
PARP1 P09874 2/20 0.47
CKS1B P61024 1/20 0.47
SKP1 P63208 1/20 0.47
SKP2 Q13309 1/20 0.47
DRD2 P14416 4/20 0.46
DRD3 P35462 1/20 0.45
BACE1 P56817 2/20 0.45
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CCR5 P51681 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
SCN9A Q15858 1/20 0.43
MCHR1 Q99705 1/20 0.43
AKT1 P31749 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7840790 0.88 CHRM2 (0.59) CHRM2CHRM1CHRM3KCNA3PARP1
SCHEMBL7960557 0.87 KCNA3 (0.50) CHRM2CHRM1CHRM3KCNA3PARP1
SCHEMBL7466823 0.86 KCNA3 (0.49) CHRM2CHRM1CHRM3KCNA3PARP1
SCHEMBL7660248 0.83 KCNA3 (0.47) CHRM2CHRM1CHRM3KCNA3PARP1
SCHEMBL7078816 0.82 DRD4 (0.58) CHRM2CHRM1CHRM3KCNA3CKS1B
SCHEMBL31052652 0.81 CKS1B (0.60) KCNA3PARP1CKS1BSKP1SKP2
SCHEMBL19820659 0.80 LMNA (0.46) KCNA3PARP1CKS1BSKP1SKP2
Formic Acid SCHEMBL7668346 0.80 KCNA3 (0.44) CHRM2CHRM1CHRM3KCNA3PARP1
SCHEMBL27226915 0.79 SIGMAR1 (0.59) CHRM2CHRM1CHRM3KCNA3PARP1
SCHEMBL18918808 0.79 PARP1 (0.57) KCNA3PARP1CKS1BSKP1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010047013-A1 Process for the preparation of arylamines LANG FENGRUI (US) 2001-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010047013-A1 Process for the preparation of arylamines AHR, NISCH, ARSA CHRM2 1365/4885CHRM1 1763/4885CHRM3 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.