Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952001 | 0.79 | MAPT (0.41) | MAPTMEN1KMT2AHPGDMAPK1 | |
| SCHEMBL98080 | 0.75 | MAPT (0.52) | EGFRBTKMAPTMEN1KMT2A | |
| SCHEMBL29210266 | 0.74 | ALDH1A1 (0.44) | EGFRBTKMAPTMEN1KMT2A | |
| SCHEMBL9788117 | 0.73 | MAPT (0.50) | EGFRBTKMAPTMEN1KMT2A | |
| SCHEMBL26032685 | 0.73 | HCAR2 (0.43) | EGFRBTKMAPTMEN1KMT2A | |
| SCHEMBL11302055 | 0.72 | MAPT (0.65) | EGFRBTKMAPTMEN1KMT2A | |
| SCHEMBL11302050 | 0.72 | MAPT (0.65) | EGFRBTKMAPTMEN1KMT2A | |
| SCHEMBL5177755 | 0.71 | SLC15A1 (0.42) | POLBRAB9A | |
| SCHEMBL5177750 | 0.71 | SLC15A1 (0.42) | POLBRAB9A | |
| SCHEMBL10526099 | 0.70 | MAPT (0.46) | MAPTMEN1KMT2AHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6267148-B1 | HEAT-AGING RESISTANCE AND OXYGENATED-GASOLINE RESISTANCE | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |