Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | CCR1 | P32246 | 3/20 | 0.53 |
| ▸ | CCR5 | P51681 | 3/20 | 0.53 |
| ▸ | CCR8 | P51685 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7236265 | 0.91 | KDM4E (0.59) | KDM4ENPC1CCR1CCR5CCR8 | |
| SCHEMBL7965339 | 0.88 | KDM4E (0.81) | KDM4ENPC1CCR1CCR5CCR8 | |
| SCHEMBL7963689 | 0.84 | KDM4E (0.75) | KDM4ENPC1CCR1CCR5CCR8 | |
| SCHEMBL4075083 | 0.82 | KDM4E (1.00) | KDM4ENPC1CCR1CCR5CCR8 | |
| SCHEMBL2061612 | 0.81 | KDM4E (0.70) | KDM4ENPC1CCR1CCR5CCR8 | |
| SCHEMBL27928516 | 0.81 | KDM4E (0.70) | KDM4ENPC1CCR1CCR5CCR8 | |
| SCHEMBL7952005 | 0.79 | KDM4E (0.68) | KDM4ENPC1CCR1CCR5CCR8 | |
| SCHEMBL323086 | 0.79 | KDM4E (0.68) | KDM4ENPC1CCR1CCR5CCR8 | |
| SCHEMBL14063447 | 0.78 | KDM4E (0.66) | KDM4ENPC1CCR1CCR5CCR8 | |
| SCHEMBL21941944 | 0.77 | METAP1 (0.57) | KDM4ENPC1CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6087510-A | Method of use of imidazolium cations | THE ROCKEFELLER UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |