SCHEMBL7963689

SCHEMBL7963689

c1ccc(-c2nc3cc4ccccc4cc3nc2-c2ccccn2)nc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.75
NPC1 O15118 3/20 0.75
LMNA P02545 4/20 0.54
MAPT P10636 4/20 0.54
KMT2A Q03164 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
PKM P14618 3/20 0.54
RAB9A P51151 2/20 0.54
CCR1 P32246 3/20 0.52
CCR5 P51681 3/20 0.52
CCR8 P51685 3/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
METAP1 P53582 1/20 0.52
BLM P54132 1/20 0.52
HIF1A Q16665 1/20 0.52
DOHH Q9BU89 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
TDP1 Q9NUW8 3/20 0.50
TP53 P04637 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7965339 0.91 KDM4E (0.81) KDM4ENPC1LMNAMAPTKMT2A
SCHEMBL4075083 0.86 KDM4E (1.00) KDM4ENPC1LMNAMAPTKMT2A
SCHEMBL2061612 0.85 KDM4E (0.70) KDM4ENPC1LMNAMAPTKMT2A
SCHEMBL27928516 0.84 KDM4E (0.70) KDM4ENPC1LMNAMAPTKMT2A
SCHEMBL7952022 0.84 KDM4E (0.70) KDM4ENPC1LMNAMAPTKMT2A
SCHEMBL7952005 0.82 KDM4E (0.68) KDM4ENPC1LMNAMAPTKMT2A
SCHEMBL323086 0.82 KDM4E (0.68) KDM4ENPC1LMNAMAPTSMN1; SMN2
SCHEMBL14063447 0.81 KDM4E (0.66) KDM4ENPC1LMNAMAPTKMT2A
SCHEMBL1104804 0.80 KDM4E (0.74) KDM4ENPC1MAPTKMT2ASMN1; SMN2
SCHEMBL19092285 0.80 KDM4E (0.64) KDM4ENPC1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190058132-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-21 US disclosed
US-7355340-B2 Quinoxaline derivatives, organic semiconductor device and electroluminescent device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-08 US disclosed
US-7355340-B2 Quinoxaline derivatives, organic semiconductor device and electroluminescent device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-08 US disclosed
US-6187928-B1 TREATING FUNGAL DISEASES THE ROCKEFELLER UNIVERSITY 2001-02-13 US disclosed
US-6087510-A Method of use of imidazolium cations THE ROCKEFELLER UNIVERSITY (US) 2000-07-11 US disclosed
US-5969150-A FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES THE ROCKEFELLER UNIVERSITY (US) 1999-10-19 US disclosed
US-5874587-A FLUORESCENCE THE ROCKEFELLER UNIVERSITY (US) 1999-02-23 US disclosed