Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.62 |
| ▸ | NQO2 | P16083 | 12/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952088 | 1.00 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2ABCB1MAPT | |
| SCHEMBL7952090 | 1.00 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2ABCB1MAPT | |
| SCHEMBL7952097 | 0.98 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2ABCB1MAPT | |
| SCHEMBL7952100 | 0.98 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2ABCB1MAPT | |
| SCHEMBL7945340 | 0.93 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7945343 | 0.93 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7945336 | 0.93 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7952134 | 0.87 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2ABCB1 | |
| SCHEMBL7952132 | 0.87 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2ABCB1 | |
| SCHEMBL1289440 | 0.86 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2ABCB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235789-B1 | GLANDULAR DISORDERS; SLEEP DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0781271-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008466-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-21 | — | — | WO | disclosed |