Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.48 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952109 | 1.00 | NFE2L2 (0.48) | NFE2L2RPS6KA2KDM4EALDH1A1MAPT | |
| SCHEMBL6752627 | 0.85 | CYP1A2 (0.44) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6752629 | 0.85 | CYP1A2 (0.44) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7952761 | 0.81 | NR1H3 (0.59) | MAOBNR1H3 | |
| SCHEMBL7951663 | 0.81 | NFE2L2 (0.53) | NFE2L2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7951657 | 0.81 | NFE2L2 (0.53) | NFE2L2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7952758 | 0.81 | NR1H3 (0.59) | MAOBNR1H3 | |
| SCHEMBL8119602 | 0.78 | PIM1 (0.43) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8119603 | 0.78 | PIM1 (0.43) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1430996 | 0.76 | CYP4F2 (0.41) | KDM4EMAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232475-B1 | REACTING A SUBSTITUTED BROMOBENZENE WITH N-VINYLIMIDE; CATALYTIC HYDROGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-15 | — | — | US | disclosed |
| EP-1013637-A2 | Process for the preparation of fluor containing phenethylamines and fluor containing beta-iminovinyl- and beta-iminoethylphenyl compounds | Bayer Aktiengesellschaft (DE) | 2000-06-28 | — | — | EP | disclosed |