Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951657 | 1.00 | NFE2L2 (0.53) | NFE2L2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7952104 | 0.81 | NFE2L2 (0.48) | NFE2L2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7952109 | 0.81 | NFE2L2 (0.48) | NFE2L2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6752629 | 0.81 | CYP1A2 (0.44) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6752627 | 0.81 | CYP1A2 (0.44) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7954348 | 0.80 | NFE2L2 (0.51) | NFE2L2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12425720 | 0.77 | ALDH1A1 (0.50) | NFE2L2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL16825154 | 0.73 | NFE2L2 (0.57) | NFE2L2KDM4EALDH1A1MAPTFBP1 | |
| SCHEMBL28753832 | 0.72 | ALDH1A1 (0.53) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL700536 | 0.72 | NFE2L2 (1.00) | NFE2L2FBP1MAOAMAOBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013637-A2 | Process for the preparation of fluor containing phenethylamines and fluor containing beta-iminovinyl- and beta-iminoethylphenyl compounds | Bayer Aktiengesellschaft (DE) | 2000-06-28 | — | — | EP | claimed |
| US-6232475-B1 | REACTING A SUBSTITUTED BROMOBENZENE WITH N-VINYLIMIDE; CATALYTIC HYDROGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-15 | — | — | US | disclosed |
| EP-1013637-A2 | Process for the preparation of fluor containing phenethylamines and fluor containing beta-iminovinyl- and beta-iminoethylphenyl compounds | Bayer Aktiengesellschaft (DE) | 2000-06-28 | — | — | EP | disclosed |