SCHEMBL7952202

SCHEMBL7952202

CC(C)(C)[Si](C)(C)OC(=O)c1cc2ccccc2cc1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
IRAK4 Q9NWZ3 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 4/20 0.37
RAB9A P51151 3/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CA12 O43570 3/20 0.37
CA9 Q16790 3/20 0.37
CA1 P00915 2/20 0.37
NCEH1 Q6PIU2 1/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
POLB P06746 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17422752 0.89 KDM4E (0.49) KDM4EALDH1A1HPGDSMN1; SMN2NPC1
SCHEMBL6870351 0.75 DRD2 (0.43) CA12CA9CA1
SCHEMBL9039997 0.74 CA12 (0.34) CA12CA9CA1
SCHEMBL20390042 0.71 LCK (0.44) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL20378759 0.71 DRD2 (0.33) CA12CA9CA1
SCHEMBL2982620 0.71 ESR1 (0.42) KDM4EALDH1A1SMN1; SMN2NPC1CA12
SCHEMBL9370159 0.70 ELANE (0.54) KDM4EALDH1A1HPGDIRAK4SMN1; SMN2
SCHEMBL8106855 0.70 KMT2A (0.52) KDM4EALDH1A1SMN1; SMN2MAPTTSHR
SCHEMBL7557304 0.70 TDP1 (0.52) ALDH1A1SMN1; SMN2MAPTTSHRMAPK1
SCHEMBL20105087 0.70 DRD2 (0.38) ALDH1A1RAB9AMAPTCA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6175043-B1 SEPARATING THE HYDROFORMYLATION REACTION PRODUCTS IN THE POLAR PHASE SOLVENT FROM THE CATALYST IN THE NON-POLAR PHASE SOLVENT, BY USING AN ORGANIC PHOSPHITE LIGAND WITH ATTACHED C9 TO C40 ALIPHATIC GROUP RENDERING THE LIGAND LIPOPHILIC E. I. DU PONT DE NEMOURS AND COMPANY 2001-01-16 US disclosed