Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582855 | 0.84 | MAPK1 (0.58) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL28301176 | 0.82 | MAPK1 (0.62) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL11199548 | 0.82 | EPAS1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL9210909 | 0.81 | MAPK1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL28299521 | 0.81 | MAPK1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL8430862 | 0.81 | MAPK1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL116971 | 0.81 | MAPK1 (0.65) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL28300949 | 0.81 | MAPK1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL4490148 | 0.81 | MAPK1 (0.61) | MAPK1MAPTALDH1A1EPAS1GAA | |
| SCHEMBL7032442 | 0.79 | MAPK1 (0.52) | MAPK1MAPTALDH1A1EPAS1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258957-B1 | INSECTICIDES, NEMATOCIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |
| CN-1192123-A | N-aryl-1, 2, 4-triazolin-5-ones | BAYER AG (DE) | 1998-09-02 | — | — | CN | disclosed |
| US-4448961-A | Substituted anilino pyrimidines | ZOECON CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |
| US-4411839-A | α-Cyano-β-(trisubstituted phenylhydrazino)-n-ethoxycarbonylacrylamides | ZOECON CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |