Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590184 | 0.75 | CYP11B2 (0.46) | CYP11B2CYP11B1MAOAKDM4ERXFP1 | |
| SCHEMBL7964663 | 0.75 | CYP11B2 (0.41) | CYP11B2CYP11B1MAOAKDM4EMAPT | |
| SCHEMBL2158233 | 0.74 | CYP11B2 (0.42) | CYP11B2CYP11B1MAOAKDM4ERXFP1 | |
| Hydrochloric Acid SCHEMBL7585391 | 0.74 | CYP11B2 (0.45) | CYP11B2CYP11B1MAOAKDM4ERXFP1 | |
| SCHEMBL2157283 | 0.74 | CYP11B2 (0.44) | CYP11B2CYP11B1MAOAKDM4ERXFP1 | |
| SCHEMBL2157245 | 0.72 | CYP11B2 (0.42) | CYP11B2CYP11B1MAOAKDM4ERXFP1 | |
| SCHEMBL2157391 | 0.72 | CYP11B2 (0.40) | CYP11B2CYP11B1MAOAKDM4EMAPT | |
| SCHEMBL2158205 | 0.71 | KDM4E (0.45) | CYP11B2CYP11B1MAOAKDM4EKMT2A | |
| SCHEMBL7592502 | 0.70 | CYP11B2 (0.42) | CYP11B2CYP11B1MAOAKDM4ERXFP1 | |
| SCHEMBL7962786 | 0.70 | CYP11B2 (0.41) | CYP11B2CYP11B1MAOAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |