Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | CTSD | P07339 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956656 | 0.95 | HCRTR1 (0.62) | HPGDHCRTR1TP53GLANAMPT | |
| SCHEMBL7954455 | 0.94 | NAMPT (0.64) | HPGDHCRTR1TP53GLANAMPT | |
| SCHEMBL7956519 | 0.91 | HPGD (0.63) | HPGDHCRTR1TP53GLANAMPT | |
| SCHEMBL11761482 | 0.89 | NAMPT (0.71) | HPGDHCRTR1TP53GLANAMPT | |
| SCHEMBL5656202 | 0.86 | HPGD (0.61) | HPGDHCRTR1TP53GLANAMPT | |
| SCHEMBL6360354 | 0.86 | TSHR (0.73) | HPGDHCRTR1TP53GLANAMPT | |
| SCHEMBL27535510 | 0.85 | HCRTR1 (0.68) | HPGDHCRTR1TP53GLANAMPT | |
| SCHEMBL7959709 | 0.84 | HPGD (0.67) | HPGDTP53GLACTSDALDH1A1 | |
| SCHEMBL11234292 | 0.84 | NAAA (0.67) | HPGDHCRTR1TP53GLANAMPT | |
| SCHEMBL2677353 | 0.84 | KMT2A (0.71) | HPGDHCRTR1TP53GLANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| CN-1262685-A | Naphthyridine derivatives | OTSUKA PHARMA CO LTD (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |