Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | CTSD | P07339 | 1/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952913 | 0.91 | HPGD (0.60) | HPGDTP53GLACTSDHCRTR1 | |
| SCHEMBL7956656 | 0.89 | HCRTR1 (0.62) | HPGDTP53GLACTSDHCRTR1 | |
| SCHEMBL7954455 | 0.88 | NAMPT (0.64) | HPGDTP53GLACTSDHCRTR1 | |
| SCHEMBL7959709 | 0.87 | HPGD (0.67) | HPGDTP53GLACTSDPOLB | |
| SCHEMBL6360123 | 0.85 | HPGD (0.65) | HPGDTP53GLACTSDHCRTR1 | |
| SCHEMBL3038950 | 0.85 | KMT2A (0.74) | HPGDTP53GLACTSDHCRTR1 | |
| SCHEMBL11761482 | 0.85 | NAMPT (0.71) | HPGDTP53GLACTSDHCRTR1 | |
| SCHEMBL10243095 | 0.84 | STAT3 (0.64) | HPGDTP53GLACTSDHCRTR1 | |
| SCHEMBL3365176 | 0.84 | CTSD (0.68) | HPGDTP53GLACTSDHCRTR1 | |
| SCHEMBL30848493 | 0.84 | HPGD (0.63) | HPGDTP53GLACTSDHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| CN-1262685-A | Naphthyridine derivatives | OTSUKA PHARMA CO LTD (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |