SCHEMBL7952969

SCHEMBL7952969

CCC(=O)Oc1ccccc1C(=O)OC

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.63
KMT2A Q03164 4/20 0.55
HTT P42858 1/20 0.55
MAPT P10636 1/20 0.54
KDM4E B2RXH2 3/20 0.53
HSD17B10 Q99714 3/20 0.53
HPGD P15428 1/20 0.53
MEN1 O00255 1/20 0.50
RECQL P46063 1/20 0.50
LMNA P02545 1/20 0.50
TSHR P16473 1/20 0.50
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SLC6A4 P31645 1/20 0.49
ALDH1A1 P00352 1/20 0.49
CFTR P13569 1/20 0.49
ATM Q13315 2/20 0.48
POLB P06746 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7864700 0.89 SLC6A3 (0.67) SLC6A3KMT2AHTTMAPTKDM4E
SCHEMBL6436076 0.88 SLC6A3 (0.65) SLC6A3KMT2AHTTMAPTKDM4E
SCHEMBL6787728 0.88 KDM4E (0.51) SLC6A3KMT2AHTTMAPTKDM4E
SCHEMBL7209919 0.87 SLC6A3 (0.59) SLC6A3KMT2AHTTMAPTKDM4E
SCHEMBL4642534 0.86 SLC6A3 (0.63) SLC6A3KMT2AHTTMAPTKDM4E
SCHEMBL7197688 0.85 TAS1R3 (0.49) SLC6A3KMT2AHTTMAPTKDM4E
SCHEMBL4647860 0.85 SLC6A3 (0.61) SLC6A3KMT2AHTTMAPTKDM4E
SCHEMBL8587612 0.85 TSHR (0.65) SLC6A3KMT2AMAPTKDM4EHSD17B10
SCHEMBL4643623 0.85 SLC6A3 (0.61) SLC6A3KMT2AHTTMAPTKDM4E
SCHEMBL7952966 0.85 KDM4E (0.49) SLC6A3KMT2AHTTMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104031015-A Preparation method for 3-methyl flavone-8-carboxylic acid JINTAN DEPEI CHEMICAL CO LTD 2014-09-10 CN disclosed
US-7666977-B2 Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-23 US disclosed
US-7557175-B2 Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-07-07 US disclosed
US-20080275206-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US disclosed
US-20080275209-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US disclosed
US-6245779-B1 ANALGESICS; ANTIINFLAMMATORY AGENTS OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2001-06-12 US disclosed
EP-0997463-A1 NAPHTHYRIDINE DERIVATIVES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2000-05-03 EP disclosed