Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168410 | 0.82 | KDM4E (0.49) | ALDH1A1LMNAMAPTEGFRNOS1 | |
| SCHEMBL29809031 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTEGFRNOS1 | |
| SCHEMBL30949914 | 0.77 | LMNA (0.43) | ALDH1A1LMNAMAPTNOS1MEN1 | |
| SCHEMBL30949966 | 0.76 | LMNA (0.42) | ALDH1A1LMNAMAPTEGFRNOS1 | |
| SCHEMBL14574648 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTEGFRNOS1 | |
| Hydrochloric Acid SCHEMBL31152319 | 0.73 | LMNA (0.41) | ALDH1A1LMNAMAPTNOS1MEN1 | |
| SCHEMBL12825893 | 0.72 | PTPN1 (0.42) | ALDH1A1LMNAMAPTNOS1TSHR | |
| SCHEMBL1461757 | 0.72 | AURKA (0.42) | ALDH1A1LMNAMAPTEGFRMEN1 | |
| SCHEMBL8132510 | 0.71 | LMNA (0.53) | ALDH1A1LMNAEGFRTSHRSMN1; SMN2 | |
| SCHEMBL30950103 | 0.71 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001517226-A | — | — | 2001-10-02 | — | — | JP | claimed |
| EP-0971925-A1 | PYRIMIDOPYRIMIDINE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 2000-01-19 | — | — | EP | claimed |
| WO-1998043974-A1 | PYRIMIDOPYRIMIDINE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 1998-10-08 | — | — | WO | claimed |