Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7810636 | 1.00 | CHRM1 (0.54) | CHRM1CHRM2 | |
| Oxalic Acid SCHEMBL7821928 | 0.95 | CHRM2 (0.52) | CHRM1CHRM2 | |
| SCHEMBL7810793 | 0.95 | CHRM1 (0.56) | CHRM1CHRM2 | |
| SCHEMBL7989374 | 0.95 | CHRM1 (0.56) | CHRM1CHRM2 | |
| SCHEMBL7818869 | 0.90 | CHRM2 (0.54) | CHRM1CHRM2 | |
| Oxalic Acid SCHEMBL7811971 | 0.88 | CHRM2 (0.61) | CHRM1CHRM2 | |
| Fumaric Acid SCHEMBL7820760 | 0.85 | CHRM2 (0.44) | CHRM1CHRM2 | |
| Fumaric Acid SCHEMBL7820759 | 0.85 | CHRM2 (0.44) | CHRM1CHRM2 | |
| SCHEMBL7818023 | 0.85 | CHRM2 (0.48) | CHRM2 | |
| SCHEMBL7810907 | 0.83 | CHRM2 (0.65) | CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281233-B1 | AZABICYCLIC RING-SUBSTITUTED THIA- OR OXADIAZOLES | NOVO NORDISK A/S (DK) | 2001-08-28 | — | — | US | disclosed |
| US-6281232-B1 | AZABICYCLIC RING-SUBSTITUTED THIA- OR OXADIAZOLES | NOVO NORDISK A/S (DK) | 2001-08-28 | — | — | US | disclosed |
| US-6271229-B1 | ADMINISTERING A 1,2,5-OXADIAZOLE COMPOUND OR 1,2,5-THIADIAZOLE COMPOUND | NOVO NORDISK A/S (DK) | 2001-08-07 | — | — | US | disclosed |
| US-6265419-B1 | IRRITABLE BOWEL DISORDER | NOVO NORDISK A/S (DK) | 2001-07-24 | — | — | US | disclosed |
| US-5710151-A | ADMINISTERING A THIADIAZOLE OR AN OXADIAZOLE DERIVATIVE TO A SUBJECT | MUHLHAUSER MARK A (US) | 1998-01-20 | — | — | US | disclosed |
| US-5612351-A | AZABICYCLIC DERIVATIVES OF 1,2,3-OXA(OR THIA)DIAZOLE | NOVO NORDISK A/S (DK) | 1997-03-18 | — | — | US | disclosed |
| WO-1996014316-A1 | A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS | NOVO NORDISK A/S (DK) | 1996-05-17 | — | — | WO | disclosed |