SCHEMBL7953241

SCHEMBL7953241

C=c1cccc/c1=c1/ccccc1=C

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.40
ALOX12 P18054 1/20 0.40
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1325235 1.00 CYP2A6 (0.40) CYP2A6ALOX12ALDH1A1CYP3A4HSD17B10
SCHEMBL58139 0.79
Ethylene SCHEMBL8984236 0.70 ALOX12 (0.39) CYP2A6ALOX12ALDH1A1CYP3A4HSD17B10
SCHEMBL29061457 0.69 ALOX12 (0.46) CYP2A6ALOX12ALDH1A1CYP3A4HSD17B10
SCHEMBL30702418 0.69 ALOX12 (0.46) CYP2A6ALOX12ALDH1A1CYP3A4HSD17B10
SCHEMBL49871 0.69 ALOX12 (0.46) CYP2A6ALOX12ALDH1A1CYP3A4HSD17B10
SCHEMBL58153 0.69 ALOX12 (0.46) CYP2A6ALOX12ALDH1A1CYP3A4HSD17B10
Naphthalene SCHEMBL4556166 0.67 CYP2A6 (0.73) CYP2A6ALOX12ALDH1A1CYP3A4HSD17B10
Carbon Monoxide SCHEMBL5589902 0.67 CYP2A6 (0.38) CYP2A6ALOX12
SCHEMBL13172092 0.67 LMNA (0.38) CYP2A6ALOX12ALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265620-B1 REACTING OLEFINIC COMPOUND WITH CARBON MONOXIDE AND HYDROGEN IN PRESENCE OF CATALYST CONTAINING METAL OF GROUP 8 TO 10 AND TRIVALENT ORANIC PHOSPHORUS COMPOUND TO PRODUCE ALDEHYDE MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-24 US disclosed