Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | CALML3 | P27482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3519370 | 0.85 | GRM2 (0.46) | GRM2MAOAMAOBF10CALML3 | |
| SCHEMBL7953621 | 0.82 | MAOB (0.43) | GRM2MAOAMAOBF10CALML3 | |
| SCHEMBL7953614 | 0.82 | MAOB (0.43) | GRM2MAOAMAOBF10CALML3 | |
| SCHEMBL7953617 | 0.82 | MAOB (0.58) | GRM2MAOAMAOBF10CALML3 | |
| SCHEMBL3117926 | 0.80 | MAOA (0.47) | GRM2MAOAMAOBF10CALML3 | |
| SCHEMBL7530454 | 0.79 | MAOB (0.51) | GRM2MAOAMAOBF10CALML3 | |
| SCHEMBL7527213 | 0.79 | MAOB (0.51) | GRM2MAOAMAOBF10CALML3 | |
| SCHEMBL7527221 | 0.79 | MAOB (0.51) | GRM2MAOAMAOBF10CALML3 | |
| SCHEMBL7530462 | 0.79 | MAOB (0.51) | GRM2MAOAMAOBF10CALML3 | |
| SCHEMBL3519365 | 0.75 | GRM2 (0.42) | GRM2MAOAMAOBF10CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255304-B1 | AIDS THERAPY | PHARMACIA & UPJOHN COMPANY | 2001-07-03 | — | — | US | disclosed |