Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.73 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.62 |
| ▸ | DHODH | Q02127 | 8/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.48 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955977 | 0.78 | MTNR1A (1.00) | TRPV1MTNR1AMTNR1BNQO2 | |
| SCHEMBL18898252 | 0.77 | TRPV1 (0.63) | TRPV1DHODHTAOK1TAOK3L3MBTL1 | |
| SCHEMBL8888114 | 0.73 | MTNR1A (0.58) | TRPV1MTNR1AMTNR1BNQO2 | |
| SCHEMBL8886980 | 0.70 | MTNR1A (0.59) | TRPV1MTNR1AMTNR1BNQO2 | |
| SCHEMBL8888224 | 0.69 | MTNR1A (0.56) | TRPV1MTNR1AMTNR1BNQO2TAOK1 | |
| SCHEMBL8431901 | 0.68 | MTNR1A (0.72) | TRPV1MTNR1AMTNR1BNQO2 | |
| SCHEMBL7951212 | 0.67 | MTNR1A (1.00) | TRPV1MTNR1AMTNR1BNQO2 | |
| SCHEMBL7950457 | 0.67 | MTNR1A (1.00) | TRPV1MTNR1AMTNR1BNQO2 | |
| SCHEMBL24087742 | 0.67 | DHODH (1.00) | TRPV1DHODHTAOK1TAOK3L3MBTL1 | |
| SCHEMBL29445361 | 0.67 | DHODH (1.00) | TRPV1DHODHTAOK1TAOK3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235789-B1 | GLANDULAR DISORDERS; SLEEP DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0781271-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008466-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-21 | — | — | WO | disclosed |