Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 15/20 | 1.00 |
| ▸ | NQO2 | P16083 | 11/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567239 | 0.83 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8916581 | 0.82 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7951392 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7951348 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7951573 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7950304 | 0.78 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL27477454 | 0.78 | MTNR1A (0.68) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7953845 | 0.78 | TRPV1 (0.73) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL7956027 | 0.76 | MTNR1A (0.85) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL29356600 | 0.74 | MTNR1A (0.59) | MTNR1AMTNR1BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235789-B1 | GLANDULAR DISORDERS; SLEEP DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0781271-B1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-06-07 | — | — | EP | disclosed |
| CN-1156443-A | Benzocycloalkene compound, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-08-06 | — | — | CN | disclosed |
| EP-0781271-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008466-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-21 | — | — | WO | disclosed |