SCHEMBL7954009

SCHEMBL7954009

Clc1[c]nc(-c2ccccc2)c(Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.41
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 5/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
HPGD P15428 3/20 0.41
GLA P06280 1/20 0.41
PKM P14618 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
GAA P10253 1/20 0.38
ALOX15 P16050 1/20 0.37
XDH P47989 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
MAPT P10636 2/20 0.35
CYP1A2 P05177 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TP53 P04637 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11884748 0.73 ALOX15 (0.40) LMNAKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL2653719 0.71 KDM4E (0.44) LMNAKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL9138181 0.65 KDM4E (0.47) LMNAKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL11806206 0.65 KDM4E (0.52) LMNAKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL23009764 0.64 KDM4E (0.71) LMNAKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL28212978 0.64 LMNA (0.54) LMNAKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL557950 0.64 KDM4E (0.42) LMNAKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL5211515 0.62 KDM4E (0.60) LMNAKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL27316158 0.62 KDM4E (0.74) LMNAKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL8835937 0.62 LMNA (0.41) LMNAKDM4EALDH1A1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211190-B1 Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
US-6200997-B1 CYCLIZATION TO GIVE OXAZOLIDINEDIONES AND TRIAZOLIDINEDIONES BASF AKTIENGESELLSCHAFT (DE) 2001-03-13 US disclosed
CN-1161687-A Phenylacetic acid alkyl esters BASF AG (DE) 1997-10-08 CN disclosed
US-5554578-A Oxime ether derivatives, their preparation and fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 1996-09-10 US disclosed
US-5468717-A Oxime ether derivatives, their preparation and fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 1995-11-21 US disclosed
US-5378711-A α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds BASF AKTIENGESELLSCHAFT (DE) 1995-01-03 US disclosed
US-5334577-A 2-(substituted pyridy-oxymethyl)-phenylglyoxylate alkyloxime BASF AKTIENGESELLSCHAFT (DE) 1994-08-02 US disclosed
US-5326767-A α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds BASF AKTIENGESELLSCHAFT (DE) 1994-07-05 US disclosed
US-5286750-A For crops or ornamental plants BASF AKTIENGESELLSCHAFT (DE) 1994-02-15 US disclosed
US-5157037-A α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds BASF AKTIENGESELLSCHAFT (DE) 1992-10-20 US disclosed