SCHEMBL7954192

SCHEMBL7954192

CCc1sc(NC=O)nc1CC(=O)O

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.34
GAA P10253 5/20 0.34
ALDH1A1 P00352 4/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
PTGDR2 Q9Y5Y4 6/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
RORC P51449 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8055684 0.78 GCK (0.41) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL1919914 0.74 PTGDR2 (0.36) MEN1KMT2APTGDR2KDM4E
SCHEMBL999293 0.72 CYP1A2 (0.47) MAPTALDH1A1MEN1KMT2APTGDR2
SCHEMBL1548493 0.72 PTGDR2 (0.38) GAAALDH1A1MEN1KMT2APTGDR2
SCHEMBL7961428 0.70 SOAT2 (0.49) MAPTALDH1A1MEN1KMT2AHSD17B10
SCHEMBL1000442 0.68 ALDH1A1 (0.40) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL11222481 0.67 MAPT (0.45) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL6608210 0.67 PTGDR2 (0.63) ALDH1A1PTGDR2HPGDKDM4E
SCHEMBL10980536 0.66 MEN1 (0.50) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL15508826 0.66 GRM4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6180238-B1 PARTICULARLY SUITABLE FOR USE IN INK JET PRINTING PROCESSES. XEROX CORPORATION 2001-01-30 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673784-B1 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORP (US) 1999-10-27 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673784-A2 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
US-6180238-B1 PARTICULARLY SUITABLE FOR USE IN INK JET PRINTING PROCESSES. XEROX CORPORATION 2001-01-30 US disclosed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP disclosed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP disclosed
EP-0673784-B1 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORP (US) 1999-10-27 EP disclosed
EP-0684509-B1 Contrast-promoting agents in graphic arts media IMATION CORP (US) 1999-10-20 EP disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
US-5494776-A CONTAINING 2,5-PIPERAZINEDIONE, GLYCOLURIL, GLUTARIMIDE OR 3-IMINOISOINDOLINONE COMPOUNDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-27 US disclosed
EP-0684510-A1 Hybrid graphic arts films with reduced occurrence of pepper fog MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-29 EP disclosed
EP-0684509-A1 Contrast-promoting agents in graphic arts media MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-29 EP disclosed
EP-0673784-A2 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORPORATION (US) 1995-09-27 EP disclosed
US-5415975-A Contrast-promoting agents in graphic arts media MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-16 US disclosed