Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310283 | 0.73 | CA12 (0.45) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL29022309 | 0.72 | CA12 (0.44) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL1150296 | 0.72 | CA12 (0.44) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL255444 | 0.71 | HSD17B10 (0.69) | KDM4EHSD17B10TSHRALOX15GAA | |
| SCHEMBL2073211 | 0.71 | HSD17B10 (0.69) | KDM4EHSD17B10TSHRALOX15GAA | |
| Hydrochloric Acid SCHEMBL1156139 | 0.69 | HSD17B10 (0.67) | KDM4EHSD17B10TSHRALOX15GAA | |
| SCHEMBL4140585 | 0.69 | L3MBTL1 (0.37) | KDM4EHSD17B10TSHRALOX15CA12 | |
| SCHEMBL13893263 | 0.68 | HSD17B10 (0.65) | KDM4EHSD17B10TSHRALOX15GAA | |
| SCHEMBL4087862 | 0.68 | CA12 (0.41) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL4163105 | 0.68 | CA12 (0.41) | KDM4ECA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258815-B1 | HETEROCYCLIC COMPOUNDS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | claimed |
| US-6258815-B1 | HETEROCYCLIC COMPOUNDS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |