Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 14/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956796 | 1.00 | EGLN1 (0.57) | EGLN1ALDH1A1SLC2A1GAARAB9A | |
| SCHEMBL13352182 | 0.81 | KLKB1 (0.52) | GAARAB9ACAPN1 | |
| SCHEMBL13320482 | 0.81 | KLKB1 (0.52) | GAARAB9ACAPN1 | |
| SCHEMBL7954435 | 0.79 | EGLN1 (0.63) | EGLN1ALDH1A1SLC2A1 | |
| SCHEMBL7954438 | 0.79 | EGLN1 (0.63) | EGLN1ALDH1A1SLC2A1 | |
| SCHEMBL4061663 | 0.76 | EGLN1 (0.66) | EGLN1ALDH1A1 | |
| SCHEMBL2143913 | 0.75 | EGLN1 (0.63) | EGLN1ALDH1A1SLC2A1RAB9A | |
| SCHEMBL2143917 | 0.75 | EGLN1 (0.63) | EGLN1ALDH1A1SLC2A1RAB9A | |
| SCHEMBL6421069 | 0.75 | GAA (0.51) | ALDH1A1GAARAB9ATACR3 | |
| SCHEMBL7691064 | 0.75 | SLC2A1 (0.68) | EGLN1ALDH1A1SLC2A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | claimed |
| US-6211376-B1 | HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-04-03 | — | — | US | disclosed |