SCHEMBL7954579

SCHEMBL7954579

C=C(C)C(=O)OC(CN)(C(C)C)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14983806 0.82 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL17708346 0.78 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL29022549 0.77 ALDH1A1 (0.42) TSHRALDH1A1THRBTDP1
SCHEMBL25561395 0.76 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL735183 0.75 ALDH1A1 (0.41) TSHRALDH1A1THRBTDP1
Hydrochloric Acid SCHEMBL4057511 0.75 ALDH1A1 (0.41) TSHRALDH1A1THRBTDP1
SCHEMBL15752775 0.74 TSHR (0.39) TSHRALDH1A1THRB
Chloromethane SCHEMBL253218 0.73 ALDH1A1 (0.39) TSHRALDH1A1THRBTDP1
SCHEMBL3817861 0.72 ALDH1A1 (0.38) TSHRALDH1A1THRBTDP1
Hydrochloric Acid SCHEMBL327263 0.72 ALDH1A1 (0.38) TSHRALDH1A1THRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005873-B2 Structured block copolymers KEMIRA OYJ (FI) 2018-06-26 US claimed
EP-3129418-A1 WATER SOLUBLE CROSS-LINKED BLOCK COPOLYMERS Kemira OYJ (FI) 2017-02-15 EP claimed
WO-2015155330-A1 WATER SOLUBLE CROSS-LINKED BLOCK COPOLYMERS KEMIRA OYJ (FI) 2015-10-15 WO claimed
US-6251554-B1 Coated carrier XEROX CORPORATION 2001-06-26 US claimed
CN-110191901-A The combination of the surfactant component and star-like macromolecules compound of sulfonation 先导聚合物技术股份有限公司 2019-08-30 CN disclosed
US-6251554-B1 Coated carrier XEROX CORPORATION 2001-06-26 US disclosed
US-6132917-A Coated carrier XEROX CORPORATION (US) 2000-10-17 US disclosed