Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 14/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 13/20 | 0.46 |
| ▸ | CASP1 | P29466 | 12/20 | 0.46 |
| ▸ | CASP7 | P55210 | 12/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 8/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 6/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128377 | 0.79 | SMO (0.41) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 | |
| SCHEMBL31128353 | 0.76 | SMO (0.45) | MEN1KMT2A | |
| SCHEMBL793832 | 0.75 | HTR2C (0.57) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 | |
| SCHEMBL23744717 | 0.75 | PTPN11 (0.42) | — | |
| SCHEMBL1694008 | 0.73 | ALDH1A1 (0.44) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 | |
| SCHEMBL291823 | 0.71 | ALDH1A1 (0.49) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 | |
| SCHEMBL10502433 | 0.70 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 | |
| SCHEMBL7311364 | 0.70 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 | |
| SCHEMBL1693963 | 0.69 | ALDH1A1 (0.46) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 | |
| SCHEMBL10721643 | 0.69 | ALDH1A1 (0.54) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405973-A2 | THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-01-18 | — | — | EP | claimed |
| WO-2010103130-A2 | NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2010-09-16 | — | — | WO | claimed |
| EP-2405973-A2 | THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-01-18 | — | — | EP | disclosed |
| WO-2011147753-A1 | ANTIVIRAL ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2011-12-01 | — | — | WO | disclosed |