Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683764 | 0.92 | RAB9A (0.39) | RAB9AHTTMEN1KMT2ANPC1 | |
| SCHEMBL5478349 | 0.80 | RAB9A (0.43) | RAB9AHTTMEN1KMT2ANPC1 | |
| SCHEMBL5475955 | 0.76 | RAB9A (0.42) | RAB9AHTTMEN1KMT2ANPC1 | |
| SCHEMBL7681793 | 0.71 | HTR1A (0.47) | — | |
| SCHEMBL1655069 | 0.67 | CA12 (0.49) | RAB9AHTTMEN1KMT2ANPC1 | |
| SCHEMBL28761808 | 0.67 | RAB9A (0.38) | RAB9AHTTMEN1KMT2ANPC1 | |
| SCHEMBL1950848 | 0.66 | TSHR (0.46) | MEN1KMT2AHIF1AL3MBTL1ALDH1A1 | |
| SCHEMBL18529408 | 0.66 | TSHR (0.46) | HTTL3MBTL1ALDH1A1MAPTAKR1B1 | |
| SCHEMBL1950032 | 0.63 | HTR1A (0.45) | RAB9ANPC1HIF1AL3MBTL1ALDH1A1 | |
| SCHEMBL30872997 | 0.63 | ACE2 (0.60) | RAB9AHTTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300354-B1 | FOR THERAPY OF NEUROLEPTIC DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-09 | — | — | US | disclosed |